|
|
7alpha-hydroxycholesterol + NAD+ <=> 7alpha-hydroxy-4-cholesten-3-one + NADH + H+
|
1.1.1.145
3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.181
cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
|
–
–
|
BMK
|
| |
BRENDA:
BR29239
KEGG:
R04263
MetaCyc:
1.1.1.181-RXN
SABIO-RK:
9288
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ <=> 7alpha-hydroxy-5beta-cholestan-3-one + NADP+
|
1.3.1.3
Delta4-3-oxosteroid 5beta-reductase
|
–
|
BMK
|
| |
BRENDA:
BS396107
KEGG:
R04817
MetaCyc:
RXN-9840
SABIO-RK:
4465
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + ferricytochrome_b5 + H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + ferricytochrome_b5 + H2O
|
1.14.18.8
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
|
–
|
MK
|
| |
KEGG:
R04826
MetaCyc:
1.14.13.95-RXN
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + NADP+ + H2O
|
1.14.18.8
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
|
–
|
|
| |
BRENDA:
BS375015
SABIO-RK:
4471
|
|
|
|
7alpha-hydroxycholesterol + NADP+ <=> 7alpha-hydroxy-4-cholesten-3-one + NADPH + H+
|
1.1.1.181
cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
|
–
|
|
| |
KEGG:
R04264
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + 6 reduced_ferredoxin_[iron-sulfur]_cluster + 6 H+ + 3 O2 <=> (25S)-7alphahydroxy-3-oxocholest-4-en-26-oate + 6 oxidized_ferredoxin + 4 H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
| |
BRENDA:
BS442991
|
|
|
|
7alpha-hydroxycholesterol + O2 <=> 7alpha-hydroxy-4-cholesten-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
|
| |
BRENDA:
BS404106
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + NADH + H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + NAD+ + H2O
|
1.14.18.8
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
|
–
|
|
| |
BRENDA:
BS376045
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + reduced_adrenodoxin + O2 <=> 7alpha,27-dihydroxy-4-cholesten-3-one + oxidized_ferredoxin + H2O
|
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
|
|
| |
BRENDA:
BS386172
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + 2 ferricytochrome_b5 + 2 H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + 2 ferricytochrome_b5 + +_H2O
|
1.14.18.8
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
|
–
|
B
|
| |
BRENDA:
BR48568
|
|
